Should I take NAC or DHM for liver protection?

It depends on your goal. NAC is better for daily liver support and chronic conditions ($6-15/month). DHM is better for alcohol-specific protection and hangover prevention ($16-32/month for 2x weekly use). Many people use both for comprehensive protection.

Can I take NAC and DHM together?

Yes, NAC and DHM work through different mechanisms and can be safely combined for enhanced liver protection. NAC supports glutathione synthesis while DHM accelerates alcohol metabolism and provides GABA modulation.

Which is better for hangovers: NAC or DHM?

DHM is specifically designed for alcohol protection and works faster (30-60 minutes vs 2-4 hours for NAC). Clinical studies show DHM reduces hangover severity by 70% and accelerates acetaldehyde breakdown. NAC is better as a general antioxidant for daily use.

What is the recommended dosage for NAC vs DHM?

NAC: 600-1200mg daily for general liver support. DHM: 300-600mg taken 30 minutes before drinking. For combination use, take NAC in the morning and DHM before alcohol consumption.

Is NAC or DHM safer for long-term use?

Both have excellent safety profiles. NAC has decades of clinical data and is FDA-approved for certain uses. DHM has GRAS status and centuries of traditional use. NAC is better studied for long-term daily use, while DHM is typically used occasionally with alcohol.

NAC vs DHM: Which Liver Supplement Works Better? [2025 Test]

2025-07-09 DHM Guide Team 10 min read

Scientific comparison of NAC and DHM for liver protection. Learn the mechanisms, benefits, and optimal use cases for each antioxidant supplement.

When it comes to protecting your liver from oxidative stress and damage, two supplements have emerged as powerful contenders: N-acetylcysteine (NAC) and dihydromyricetin (DHM). Both offer unique mechanisms of action and proven benefits, but understanding their differences is crucial for making an informed choice about which antioxidant supplement best suits your liver protection needs.